HOCl technology

What is hypochlorous acid?

Hypochlorous acid is a weak acid made of chlorine and water. It also occurs in the body: certain immune cells produce it themselves. In aqueous solution it exists in equilibrium with hypochlorite, depending on the pH. At a pH of around 6.5, free chlorine is present predominantly as hypochlorous acid (HOCl); as the pH rises, the proportion of hypochlorite (OCl⁻) increases (pKa ≈ 7.5).

Sanocyn forte is not bleach. The rinsing and cleansing products have a pH close to neutral.

Literature on the substance (not a product claim)

The following information concerns only the substance hypochlorous acid or other preparations. It is not a statement about Sanocyn products.

The interdisciplinary consensus “Consensus on Wound Antisepsis” (Kramer A, Dissemond J, Kim S, Willy C, Mayer D, Papke R, Tuchmann F, Assadian O. Consensus on Wound Antisepsis: Update 2018. Skin Pharmacol Physiol 2018;31:28–58) evaluates active substances for wound care in human medicine. In its indication-based recommendation, hypochlorite (NaOCl/HOCl) is named as a recommended active substance in four of nine indications. The recommendations relate to preparations used in human medicine; Sanocyn forte is a care product, not a medicinal product, and is not the subject of this evaluation.

Production

The products are made in a proprietary electrochemical process. A saline solution flows through electrolysis cells, and hypochlorous acid forms.

• Produced and filled in Austria and Germany.
• The manufacturer is Loxotec GmbH, Vienna. The quality management system for development and international distribution is certified to ISO 9001:2015 (TÜV SÜD, certificate Q1531439/02, valid until 31 January 2028).
• Developed with veterinarians.

Composition

The rinsing and cleansing products (excluding HOCl Derma Shampoo; details on Sanocyn Pro according to the product information) contain:

• water
• sodium chloride
• active chlorine released from hypochlorous acid: 0.5 g/l (< 0.1 % w/v; Solution, Hydrogel, Ear Cleaner and Eye Cleaner)

The hydrogels additionally contain a layered silicate (LiMgNa silicate). It provides the gel structure and helps the gel adhere to the skin.

The rinsing and cleansing products (excluding HOCl Derma Shampoo; details on Sanocyn Pro according to the product information) contain no alcohol, antibiotics, colourings or fragrances. A faint smell of chlorine is noticeable.

HOCl Derma Shampoo is a two-chamber product (200 ml): chamber 1 contains a care shampoo, chamber 2 a gel containing hypochlorous acid (HOCl). The ingredients are listed separately by chamber.

• Chamber 1 (care shampoo): Aqua, Sodium Laureth Sulfate, Glycerin, Cocamidopropyl Betaine, Sodium Chloride, Panthenol, Phenoxyethanol, Alcohol denat., Lactic Acid, Arginine, Lavandula Oil/Extract, Oryza Sativa Extract, Phenethyl Alcohol, Hydrolyzed Wheat Protein, Proline, Naringin, Alanine, Ferulic Acid, Malic Acid, Rosmarinus Officinalis Extract, Sodium Lactate, Humulus Lupulus Extract, Calendula Officinalis Extract, Equisetum Arvense Extract, Serine, Rosmarinic Acid, Biotin, Rosmarinus Officinalis Oil, Rutin, Citric Acid
• Chamber 2 (HOCl gel): Aqua, Lithium Magnesium Sodium Silicate, Sodium Chloride, Active Chlorine released from Hypochlorous Acid

pH value

Sanocyn forte has a pH of approx. 6.5 (near-neutral). The rinsing and cleansing products (excluding HOCl Derma Shampoo; details on Sanocyn Pro according to the product information) contain no alcohol.

Skin tolerance

Sanocyn forte Solution and Hydrogel were classified as non-irritant to skin in the in vitro skin irritation test according to ISO 10993-10 / OECD 439 (reconstructed human epidermis; TentaMedix GmbH, DAkkS-accredited, 2019). This statement applies to the Solution and Hydrogel only. On very sensitive skin, irritation may nevertheless occur.

Shelf life

Shelf life: unopened 24 months, after opening 3 months (per stability data). High temperatures over many hours can reduce the active chlorine content. Store at room temperature (not above 25 °C) and protect from direct sunlight.

Principle of use: rinse and protect

Solution and hydrogel are designed as a system.

1. Rinse. The solution cleanses and rinses the area. It loosens crusts, secretions and dirt.

2. Protect. The hydrogel adheres for a long time, keeps the area moist and forms a protective film.

Using both products together is the recommended application.

Evidence library in the Professionals area

Studies, stability data, safety data sheets and the case library are available to verified veterinarians in the Professionals area.

Go to the Professionals area

Downloads

The product information is public and available without registration.

• Product information Sanocyn forte Solution (PDF)
• Product information Sanocyn forte Hydrogel (PDF)
• Product information Sanocyn forte Ear Cleaner (PDF)
• Product information Sanocyn forte Eye Cleaner (PDF)
• Product information Sanocyn dental Hygiene Spray (PDF)
• Product information Sanocyn dental Finger Toothbrush (PDF)
• Product information Sanocyn forte Preputial Cleaner (PDF)
• Product information HOCl Derma Shampoo (PDF)
• Product information Sanocyn Pro (PDF)

Sanocyn forte, Sanocyn dental, Sanocyn Pro and HOCl Derma Shampoo are care products. They are not veterinary medicinal products, biocides or medical devices.